儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0652R
特異性: Endogenous
基因名稱: TBC1D4
蛋白名稱: TBC1 domain family member 4
別名: TBC1D4;AS160;KIAA0603;TBC1 domain family member 4;Akt substrate of 160 kDa;AS160
Organism-1: 人
基因ID-1: 9882
SwissProt-1: O60343
Organism-2: Mouse
基因ID-2: 210789
SwissProt-2: Q8BYJ6
細(xì)胞定位: Cytoplasm
組織表達(dá): Widely expressed. Isoform 2 is the highest overexpressed in most tissues. Isoform 1 is highly expressed in skeletal muscle and heart, but was not detectable in the liver nor in adipose tissue. Isoform 2 is strongly expressed in adrenal and thyroid gland, and also in lung, kidney, colon, brain and adipose tissue. Isoform 2 is moderately expressed in skeletal muscle. Expressed in pancreatic Langerhans islets, including beta cells (at protein level). Expression is decreased by twofold in pancreatic islets in type 2 diabetes patients compared to control subjects. Up-regulated in T-cells from patients with atopic dermatitis.
儲存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號: PT0652R
特異性: Endogenous
基因名稱: TBC1D4
蛋白名稱: TBC1 domain family member 4
別名: TBC1D4;AS160;KIAA0603;TBC1 domain family member 4;Akt substrate of 160 kDa;AS160
Organism-1: 人
基因ID-1: 9882
SwissProt-1: O60343
Organism-2: Mouse
基因ID-2: 210789
SwissProt-2: Q8BYJ6
細(xì)胞定位: Cytoplasm
組織表達(dá): Widely expressed. Isoform 2 is the highest overexpressed in most tissues. Isoform 1 is highly expressed in skeletal muscle and heart, but was not detectable in the liver nor in adipose tissue. Isoform 2 is strongly expressed in adrenal and thyroid gland, and also in lung, kidney, colon, brain and adipose tissue. Isoform 2 is moderately expressed in skeletal muscle. Expressed in pancreatic Langerhans islets, including beta cells (at protein level). Expression is decreased by twofold in pancreatic islets in type 2 diabetes patients compared to control subjects. Up-regulated in T-cells from patients with atopic dermatitis.