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AIFM1 (PT0650R) PT® Rabbit mAb
商品貨號(hào)： PLR10096
適 應(yīng) 性： 人,小鼠,大鼠,
WB IHC IF ELISA IP
￥1200元
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說(shuō)明書(shū)
商品描述
  • 靶點(diǎn)-Target： AIFM1
  • MW(Calculated)： 67kD
  • MW(Observed)： 67kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 修飾-Modification： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0650R
  • 特異性： Endogenous
  • 基因名稱(chēng)： AIFM1 ALF PDCD8
  • 蛋白名稱(chēng)： Apoptosis-inducing factor 1 mitochondrial
  • 別名： AIFM1;AIF;PDCD8;Apoptosis-inducing factor 1;mitochondrial;Programmed cell death protein 8
  • Organism-1： 人
  • 基因ID-1： 9131
  • SwissProt-1： O95831
  • Organism-2： Mouse
  • 基因ID-2： 26926
  • SwissProt-2： Q9Z0X1
  • Organism-3： Rat
  • 基因ID-3： 83533
  • SwissProt-3： Q9JM53
  • 細(xì)胞定位： Mitochondrion intermembrane space . Mitochondrion inner membrane. Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis (PubMed:15775970). Colocalizes with EIF3G in the nucleus and perinuclear region (PubMed:17094969). .; [Isoform 3]: Mitochondrion intermembrane space . Mitochondrion inner membrane . Has a stronger membrane anchorage than isoform 1. .; [Isoform 4]: Mitochondrion . Cytoplasm, cytosol . In pro-apoptotic conditions, is released from mitochondria to cytosol in a calpain/cathepsin-dependent manner. .; [Isoform 5]: Cytoplasm .
  • 組織表達(dá)： Expressed in all tested tissues (PubMed:16644725). Detected in muscle and skin fibroblasts (at protein level) (PubMed:23217327). Expressed in osteoblasts (at protein level) (PubMed:28842795). ; [Isoform 3]: Brain specific. ; [Isoform 4]: Expressed in all tested tissues except brain. ; [Isoform 5]: Isoform 5 is frequently down-regulated in 人 cancers.
AIFM1 (PT0650R) PT® Rabbit mAb
Catalog No PLR10096
Product information
  • 靶點(diǎn)-Target： AIFM1
  • MW(Calculated)： 67kD
  • MW(Observed)： 67kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 修飾-Modification： Unmodified
  • 推薦稀釋比： IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號(hào)： PT0650R
  • 特異性： Endogenous
  • 基因名稱(chēng)： AIFM1 ALF PDCD8
  • 蛋白名稱(chēng)： Apoptosis-inducing factor 1 mitochondrial
  • 別名： AIFM1;AIF;PDCD8;Apoptosis-inducing factor 1;mitochondrial;Programmed cell death protein 8
  • Organism-1： 人
  • 基因ID-1： 9131
  • SwissProt-1： O95831
  • Organism-2： Mouse
  • 基因ID-2： 26926
  • SwissProt-2： Q9Z0X1
  • Organism-3： Rat
  • 基因ID-3： 83533
  • SwissProt-3： Q9JM53
  • 細(xì)胞定位： Mitochondrion intermembrane space . Mitochondrion inner membrane. Cytoplasm . Nucleus . Cytoplasm, perinuclear region . Proteolytic cleavage during or just after translocation into the mitochondrial intermembrane space (IMS) results in the formation of an inner-membrane-anchored mature form (AIFmit). During apoptosis, further proteolytic processing leads to a mature form, which is confined to the mitochondrial IMS in a soluble form (AIFsol). AIFsol is released to the cytoplasm in response to specific death signals, and translocated to the nucleus, where it induces nuclear apoptosis (PubMed:15775970). Colocalizes with EIF3G in the nucleus and perinuclear region (PubMed:17094969). .; [Isoform 3]: Mitochondrion intermembrane space . Mitochondrion inner membrane . Has a stronger membrane anchorage than isoform 1. .; [Isoform 4]: Mitochondrion . Cytoplasm, cytosol . In pro-apoptotic conditions, is released from mitochondria to cytosol in a calpain/cathepsin-dependent manner. .; [Isoform 5]: Cytoplasm .
  • 組織表達(dá)： Expressed in all tested tissues (PubMed:16644725). Detected in muscle and skin fibroblasts (at protein level) (PubMed:23217327). Expressed in osteoblasts (at protein level) (PubMed:28842795). ; [Isoform 3]: Brain specific. ; [Isoform 4]: Expressed in all tested tissues except brain. ; [Isoform 5]: Isoform 5 is frequently down-regulated in 人 cancers.
    • Hunan UPT Biotechnology Co.,Ltd
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    E-mail：service@uptbio.com
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