儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0659R
特異性: Endogenous
基因名稱: PARK2
蛋白名稱: E3 ubiquitin-protein ligase parkin
別名: PARK2;PRKN;E3 ubiquitin-protein ligase parkin;Parkinson juvenile disease protein 2;Parkinson disease protein 2
Organism-1: 人
基因ID-1: 5071
SwissProt-1: O60260
Organism-2: Mouse
SwissProt-2: Q9WVS6
細(xì)胞定位: Cytoplasm
組織表達(dá): Highly expressed in the brain including the substantia nigra (PubMed:9560156, PubMed:19501131). Expressed in heart, testis and skeletal muscle (PubMed:9560156). Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients (PubMed:14614460, PubMed:12719539). Overexpression protects dopamine neurons from kainate-mediated apoptosis (PubMed:12628165). Found in serum (at protein level) (PubMed:19501131).
儲(chǔ)存: -15°C to -25°C/1 year(Do not lower than -25°C)
克隆性: Monoclonal
克隆號(hào): PT0659R
特異性: Endogenous
基因名稱: PARK2
蛋白名稱: E3 ubiquitin-protein ligase parkin
別名: PARK2;PRKN;E3 ubiquitin-protein ligase parkin;Parkinson juvenile disease protein 2;Parkinson disease protein 2
Organism-1: 人
基因ID-1: 5071
SwissProt-1: O60260
Organism-2: Mouse
SwissProt-2: Q9WVS6
細(xì)胞定位: Cytoplasm
組織表達(dá): Highly expressed in the brain including the substantia nigra (PubMed:9560156, PubMed:19501131). Expressed in heart, testis and skeletal muscle (PubMed:9560156). Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients (PubMed:14614460, PubMed:12719539). Overexpression protects dopamine neurons from kainate-mediated apoptosis (PubMed:12628165). Found in serum (at protein level) (PubMed:19501131).