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ADAM10 (PT0709R) PT® Rabbit mAb
商品貨號： PLR10002
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC IF ELISA IP
￥1200元
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  • 靶點(diǎn)-Target： ADAM10
  • MW(Calculated)： 84kD
  • MW(Observed)： 84kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 修飾-Modification： Unmodified
  • 推薦稀釋比： IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0709R
  • 特異性： Endogenous
  • 基因名稱： ADAM10
  • 蛋白名稱： Disintegrin and metalloproteinase domain-containing protein 10
  • 別名： ADAM10;KUZ;MADM;Disintegrin and metalloproteinase domain-containing protein 10;ADAM 10;CDw156;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;CD156c
  • Organism-1： 人
  • 基因ID-1： 102
  • SwissProt-1： O14672
  • Organism-2： Mouse
  • 基因ID-2： 11487
  • SwissProt-2： O35598
  • Organism-3： Rat
  • SwissProt-3： Q10743
  • 細(xì)胞定位： Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011). .
  • 組織表達(dá)： Expressed in the brain (at protein level) (PubMed:23676497). Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver (PubMed:11511685, PubMed:9016778).
ADAM10 (PT0709R) PT® Rabbit mAb
Catalog No PLR10002
Product information
  • 靶點(diǎn)-Target： ADAM10
  • MW(Calculated)： 84kD
  • MW(Observed)： 84kD
  • 宿主物種-Host Species： Rabbit
  • 同種型-Isotype： IgG,Kappa
  • 修飾-Modification： Unmodified
  • 推薦稀釋比： IHC 1:200-1:2000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
  • 組成： PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
  • 純化工藝： Protein A
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 克隆性： Monoclonal
  • 克隆號： PT0709R
  • 特異性： Endogenous
  • 基因名稱： ADAM10
  • 蛋白名稱： Disintegrin and metalloproteinase domain-containing protein 10
  • 別名： ADAM10;KUZ;MADM;Disintegrin and metalloproteinase domain-containing protein 10;ADAM 10;CDw156;Kuzbanian protein homolog;Mammalian disintegrin-metalloprotease;CD156c
  • Organism-1： 人
  • 基因ID-1： 102
  • SwissProt-1： O14672
  • Organism-2： Mouse
  • 基因ID-2： 11487
  • SwissProt-2： O35598
  • Organism-3： Rat
  • SwissProt-3： Q10743
  • 細(xì)胞定位： Cell membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle . Cell projection, axon . Cell projection, dendrite . Cell junction, adherens junction . Cytoplasm . Is localized in the plasma membrane but is also expressed in the Golgi apparatus and in clathrin-coated vesicles derived likely from the Golgi (PubMed:12475894). During long term depression, it is recruited to the cell membrane by DLG1 (PubMed:23676497). The immature form is mainly located near cytoplasmic fibrillar structures, while the mature form is predominantly located at zonula adherens and the cell membrane (PubMed:30463011). The localization and clustering of mature ADAM10 to zonula adherens is regulated by AFDN, TSPAN33, PLEKHA7 and PDZD11 (PubMed:30463011). .
  • 組織表達(dá)： Expressed in the brain (at protein level) (PubMed:23676497). Expressed in spleen, lymph node, thymus, peripheral blood leukocyte, bone marrow, cartilage, chondrocytes and fetal liver (PubMed:11511685, PubMed:9016778).
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