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METL8 rabbit pAb
商品貨號(hào)： PLA021561
適 應(yīng) 性： 人,小鼠
WB IHC
￥600元
規(guī)格：
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MSDS
說(shuō)明書(shū)
商品描述
  • 基因名稱： METTL8
  • 蛋白名稱： Methyltransferase-like protein 8 (EC 2.1.1.-)
  • Human_swiss_prot_no： Q9H825
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9H825/entry
  • Mouse_gene_id： 228019
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228019
  • Mouse_swiss_prot_no： A2AUU0
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/A2AUU0/entry
  • 特異性： This antibody detects endogenous levels of METL8 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Methyltransferase-like protein 8 (EC 2.1.1.-)
  • 分子量： 32kD
  • 功能： Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of mitochondrial tRNA(Ser)(UCN) and tRNA(Thr) . N(3)-methylcytidine methylation modification regulates mitochondrial translation efficiency and is required for activity of the respiratory chain . N(3)-methylcytidine methylation of mitochondrial tRNA(Ser)(UCN) requires the formation of N(6)-dimethylallyladenosine(37) (i6A37) by TRIT1 as prerequisite . May also mediate N(3)-methylcytidine modification of mRNAs . The existence of N(3)-methylcytidine modification on mRNAs is however unclear, and additional evidences are required to confirm the role of the N(3)-methylcytidine-specific mRNA methyltransferase activity of METTL8 in vivo .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Mitochondrion . Mitochondrial protein: the cytoplasmic or nuclear localization observed by some groups is either the result of an incorrect localization caused by N-terminal tagging that interferes with mitochondrial targeting, or splice isoforms that lack the N-terminal mitochondrial transit sequence. .
  • 科研貨號(hào)： PLA021561
METL8 rabbit pAb
Catalog No PLA021561
Product information
  • 基因名稱： METTL8
  • 蛋白名稱： Methyltransferase-like protein 8 (EC 2.1.1.-)
  • Human_swiss_prot_no： Q9H825
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9H825/entry
  • Mouse_gene_id： 228019
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=228019
  • Mouse_swiss_prot_no： A2AUU0
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/A2AUU0/entry
  • 特異性： This antibody detects endogenous levels of METL8 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Methyltransferase-like protein 8 (EC 2.1.1.-)
  • 分子量： 32kD
  • 功能： Mitochondrial S-adenosyl-L-methionine-dependent methyltransferase that mediates N(3)-methylcytidine modification of residue 32 of the tRNA anticodon loop of mitochondrial tRNA(Ser)(UCN) and tRNA(Thr) . N(3)-methylcytidine methylation modification regulates mitochondrial translation efficiency and is required for activity of the respiratory chain . N(3)-methylcytidine methylation of mitochondrial tRNA(Ser)(UCN) requires the formation of N(6)-dimethylallyladenosine(37) (i6A37) by TRIT1 as prerequisite . May also mediate N(3)-methylcytidine modification of mRNAs . The existence of N(3)-methylcytidine modification on mRNAs is however unclear, and additional evidences are required to confirm the role of the N(3)-methylcytidine-specific mRNA methyltransferase activity of METTL8 in vivo .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Mitochondrion . Mitochondrial protein: the cytoplasmic or nuclear localization observed by some groups is either the result of an incorrect localization caused by N-terminal tagging that interferes with mitochondrial targeting, or splice isoforms that lack the N-terminal mitochondrial transit sequence. .
  • 科研貨號(hào)： PLA021561
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