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WWP1 rabbit pAb
商品貨號： PLA021559
適 應(yīng) 性： 人,小鼠
WB IHC
￥600元
規(guī)格：
在線咨詢
MSDS
說明書
商品描述
  • 基因名稱： WWP1
  • 蛋白名稱： NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (Atrophin-1-interacting protein 5) (AIP5) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
  • Human_gene_id： 11059
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11059
  • Human_swiss_prot_no： Q9H0M0
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9H0M0/entry
  • Mouse_gene_id： 107568
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107568
  • Mouse_swiss_prot_no： Q8BZZ3
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BZZ3/entry
  • 特異性： This antibody detects endogenous levels of WWP1 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (Atrophin-1-interacting protein 5) (AIP5) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
  • 分子量： 101kD
  • 功能： E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein . Nucleus .
  • 組織表達(dá)： Detected in heart, placenta, pancreas, kidney, liver, skeletal muscle, bone marrow, fetal brain, and at much lower levels in adult brain and lung. Isoform 1 and isoform 5 predominate in all tissues tested, except in testis and bone marrow, where isoform 5 is expressed at much higher levels than isoform 1.
  • 科研貨號： PLA021559
WWP1 rabbit pAb
Catalog No PLA021559
Product information
  • 基因名稱： WWP1
  • 蛋白名稱： NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (Atrophin-1-interacting protein 5) (AIP5) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
  • Human_gene_id： 11059
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11059
  • Human_swiss_prot_no： Q9H0M0
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9H0M0/entry
  • Mouse_gene_id： 107568
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107568
  • Mouse_swiss_prot_no： Q8BZZ3
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BZZ3/entry
  • 特異性： This antibody detects endogenous levels of WWP1 at Human, Mouse
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 6.3.2.-) (Atrophin-1-interacting protein 5) (AIP5) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
  • 分子量： 101kD
  • 功能： E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates ERBB4 isoforms JM-A CYT-1 and JM-B CYT-1, KLF2, KLF5 and TP63 and promotes their proteasomal degradation. Ubiquitinates RNF11 without targeting it for degradation. Ubiquitinates and promotes degradation of TGFBR1; the ubiquitination is enhanced by SMAD7. Ubiquitinates SMAD6 and SMAD7. Ubiquitinates and promotes degradation of SMAD2 in response to TGF-beta signaling, which requires interaction with TGIF.
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein . Nucleus .
  • 組織表達(dá)： Detected in heart, placenta, pancreas, kidney, liver, skeletal muscle, bone marrow, fetal brain, and at much lower levels in adult brain and lung. Isoform 1 and isoform 5 predominate in all tissues tested, except in testis and bone marrow, where isoform 5 is expressed at much higher levels than isoform 1.
  • 科研貨號： PLA021559
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