功能: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cell membrane ; Multi-pass membrane protein .
組織表達(dá): Widely expressed with highest levels in brain and immune tissues.
功能: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells .
相關(guān)產(chǎn)品: RS0001,RS0002,YM3028,YM3029
細(xì)胞定位: Cell membrane ; Multi-pass membrane protein .
組織表達(dá): Widely expressed with highest levels in brain and immune tissues.