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STIM1 rabbit pAb
商品貨號： PLA021533
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： STIM1 GOK
  • 蛋白名稱： Stromal interaction molecule 1
  • Human_gene_id： 6786
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6786
  • Human_swiss_prot_no： Q13586
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q13586/entry
  • Mouse_gene_id： 20866
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20866
  • Mouse_swiss_prot_no： P70302
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P70302/entry
  • Rat_gene_id： 361618
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361618
  • Rat_swiss_prot_no： P84903
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P84903/entry
  • 特異性： This antibody detects endogenous levels of STIM1 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Stromal interaction molecule 1
  • 分子量： 75kD
  • 功能： Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cell membrane; Single-pass type I membrane protein . Endoplasmic reticulum membrane; Single-pass type I membrane protein . Cytoplasm, cytoskeleton . Sarcoplasmic reticulum . Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane (PubMed:19249086, PubMed:16005298, PubMed:16208375, PubMed:18854159). Associated with the microtubule network at the growing distal tip of microtubules (PubMed:19632184). Colocalizes with ORAI1 at the cell membrane (PubMed:27185316). Colocalizes preferentially with CASQ1 at endoplasmic reticulum in response to a depletion of intracellular calcium (PubMed:27185316). .
  • 組織表達(dá)： Ubiquitously expressed in various human primary cells and tumor cell lines.
  • 科研貨號： PLA021533
STIM1 rabbit pAb
Catalog No PLA021533
Product information
  • 基因名稱： STIM1 GOK
  • 蛋白名稱： Stromal interaction molecule 1
  • Human_gene_id： 6786
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6786
  • Human_swiss_prot_no： Q13586
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q13586/entry
  • Mouse_gene_id： 20866
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20866
  • Mouse_swiss_prot_no： P70302
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P70302/entry
  • Rat_gene_id： 361618
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=361618
  • Rat_swiss_prot_no： P84903
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P84903/entry
  • 特異性： This antibody detects endogenous levels of STIM1 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Stromal interaction molecule 1
  • 分子量： 75kD
  • 功能： Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores . Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit ORAI1 . Involved in enamel formation . Activated following interaction with STIMATE, leading to promote STIM1 conformational switch .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cell membrane; Single-pass type I membrane protein . Endoplasmic reticulum membrane; Single-pass type I membrane protein . Cytoplasm, cytoskeleton . Sarcoplasmic reticulum . Translocates from the endoplasmic reticulum to the cell membrane in response to a depletion of intracellular calcium and is detected at punctae corresponding to junctions between the endoplasmic reticulum and the cell membrane (PubMed:19249086, PubMed:16005298, PubMed:16208375, PubMed:18854159). Associated with the microtubule network at the growing distal tip of microtubules (PubMed:19632184). Colocalizes with ORAI1 at the cell membrane (PubMed:27185316). Colocalizes preferentially with CASQ1 at endoplasmic reticulum in response to a depletion of intracellular calcium (PubMed:27185316). .
  • 組織表達(dá)： Ubiquitously expressed in various human primary cells and tumor cell lines.
  • 科研貨號： PLA021533
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