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UBL4A rabbit pAb
商品貨號： PLA021520
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC
￥600元
規(guī)格：
在線咨詢
MSDS
說明書
商品描述
  • 基因名稱： UBL4A DXS254E GDX UBL4
  • 蛋白名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
  • Human_gene_id： 8266
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8266
  • Human_swiss_prot_no： P11441
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P11441/entry
  • Mouse_gene_id： 27643
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27643
  • Mouse_swiss_prot_no： P21126
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P21126/entry
  • Rat_gene_id： 293864
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293864
  • Rat_swiss_prot_no： B2GV38
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/B2GV38/entry
  • 特異性： This antibody detects endogenous levels of UBL4A at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
  • 分子量： 17kD
  • 功能： As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum . The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細胞定位： Cytoplasm, cytosol . Nucleus .
  • 科研貨號： PLA021520
UBL4A rabbit pAb
Catalog No PLA021520
Product information
  • 基因名稱： UBL4A DXS254E GDX UBL4
  • 蛋白名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
  • Human_gene_id： 8266
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8266
  • Human_swiss_prot_no： P11441
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P11441/entry
  • Mouse_gene_id： 27643
  • Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=27643
  • Mouse_swiss_prot_no： P21126
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P21126/entry
  • Rat_gene_id： 293864
  • Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=293864
  • Rat_swiss_prot_no： B2GV38
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/B2GV38/entry
  • 特異性： This antibody detects endogenous levels of UBL4A at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000 IHC 1:50-200
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Ubiquitin-like protein 4A (Ubiquitin-like protein GDX)
  • 分子量： 17kD
  • 功能： As part of a cytosolic protein quality control complex, the BAG6/BAT3 complex, maintains misfolded and hydrophobic patches-containing proteins in a soluble state and participates in their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation . The BAG6/BAT3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Recruited to ribosomes, it interacts with the transmembrane region of newly synthesized tail-anchored proteins and together with SGTA and ASNA1 mediates their delivery to the endoplasmic reticulum . Client proteins that cannot be properly delivered to the endoplasmic reticulum are ubiquitinated and sorted to the proteasome . Similarly, the BAG6/BAT3 complex also functions as a sorting platform for proteins of the secretory pathway that are mislocalized to the cytosol either delivering them to the proteasome for degradation or to the endoplasmic reticulum . The BAG6/BAT3 complex also plays a role in the endoplasmic reticulum-associated degradation (ERAD), a quality control mechanism that eliminates unwanted proteins of the endoplasmic reticulum through their retrotranslocation to the cytosol and their targeting to the proteasome. It maintains these retrotranslocated proteins in an unfolded yet soluble state condition in the cytosol to ensure their proper delivery to the proteasome .
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細胞定位： Cytoplasm, cytosol . Nucleus .
  • 科研貨號： PLA021520
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