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RSK2 rabbit pAb
商品貨號(hào)： PLA021477
適 應(yīng) 性： 人,小鼠,大鼠
WB
￥600元
規(guī)格：
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MSDS
說(shuō)明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： RPS6KA3 ISPK1 MAPKAPK1B RSK2
  • 蛋白名稱： RSK2
  • Human_gene_id： 6197
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6197
  • Human_swiss_prot_no： P51812
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P51812/entry
  • Mouse_gene_id： 110651
  • Mouse_gene_link： https://www.uniprot.org/uniprot/110651
  • Mouse_swiss_prot_no： P18654
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P18654
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of RSK2 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
  • 分子量： 81kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in RPS6KA3 are the cause of Coffin-Lowry syndrome (CLS) [MIM:303600]; an X-linked dominant disorder characterized by severe mental retardation with facial and digital dysmorphisms, and progressive skeletal deformations.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-386, as part of the activation process.,PTM:Ser-227 phosphorylation promotes Ser-386 phosphorylation and leads to basal activation. Full activation by growth factors requires additional phosphorylation on Ser-369.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity). Interacts with NFATC4.,tissue specificity:Expressed in many tissues, highest levels in skeletal muscle.,
  • 細(xì)胞定位： Nucleus . Cytoplasm .
  • 組織表達(dá)： Expressed in many tissues, highest levels in skeletal muscle.
  • 科研貨號(hào)： PLA021477
RSK2 rabbit pAb
Catalog No PLA021477
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： RPS6KA3 ISPK1 MAPKAPK1B RSK2
  • 蛋白名稱： RSK2
  • Human_gene_id： 6197
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6197
  • Human_swiss_prot_no： P51812
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P51812/entry
  • Mouse_gene_id： 110651
  • Mouse_gene_link： https://www.uniprot.org/uniprot/110651
  • Mouse_swiss_prot_no： P18654
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P18654
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of RSK2 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Ribosomal protein S6 kinase alpha-3 (S6K-alpha-3) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 3) (p90-RSK 3) (p90RSK3) (Insulin-stimulated protein kinase 1) (ISPK-1) (MAP kinase-activated protein kinase 1b) (MAPK-activated protein kinase 1b) (MAPKAP kinase 1b) (MAPKAPK-1b) (Ribosomal S6 kinase 2) (RSK-2) (pp90RSK2)
  • 分子量： 81kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,disease:Defects in RPS6KA3 are the cause of Coffin-Lowry syndrome (CLS) [MIM:303600]; an X-linked dominant disorder characterized by severe mental retardation with facial and digital dysmorphisms, and progressive skeletal deformations.,enzyme regulation:Activated by multiple phosphorylations on threonine and serine residues.,function:Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.,PTM:Autophosphorylated on Ser-386, as part of the activation process.,PTM:Ser-227 phosphorylation promotes Ser-386 phosphorylation and leads to basal activation. Full activation by growth factors requires additional phosphorylation on Ser-369.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells. Transiently dissociates following mitogenic stimulation (By similarity). Interacts with NFATC4.,tissue specificity:Expressed in many tissues, highest levels in skeletal muscle.,
  • 細(xì)胞定位： Nucleus . Cytoplasm .
  • 組織表達(dá)： Expressed in many tissues, highest levels in skeletal muscle.
  • 科研貨號(hào)： PLA021477
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