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TPPP rabbit pAb
商品貨號： PLA021474
適 應(yīng) 性： 人,小鼠,大鼠
WB
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： TPPP TPPP1
  • 蛋白名稱： TPPP
  • Human_gene_id： 11076
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11076
  • Human_swiss_prot_no： O94811
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/O94811/entry
  • Mouse_gene_id： 72948
  • Mouse_gene_link： https://www.uniprot.org/uniprot/72948
  • Mouse_swiss_prot_no： Q7TQD2
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q7TQD2
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of TPPP at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)
  • 分子量： 24kD
  • 功能： function:Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,similarity:Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed.,
  • 細(xì)胞定位： Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton . Nucleus . Cytoplasm, cytoskeleton, spindle . Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies (PubMed:15590652, PubMed:17027006). During mitosis, colocalizes with LIMK2 at the mitotic spindle (PubMed:22328514). .
  • 組織表達： Widely expressed.
  • 科研貨號： PLA021474
TPPP rabbit pAb
Catalog No PLA021474
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： TPPP TPPP1
  • 蛋白名稱： TPPP
  • Human_gene_id： 11076
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11076
  • Human_swiss_prot_no： O94811
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/O94811/entry
  • Mouse_gene_id： 72948
  • Mouse_gene_link： https://www.uniprot.org/uniprot/72948
  • Mouse_swiss_prot_no： Q7TQD2
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q7TQD2
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of TPPP at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Tubulin polymerization-promoting protein (TPPP) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)
  • 分子量： 24kD
  • 功能： function:Promotes in vitro the polymerization of tubulin into double-walled tubules and polymorphic aggregates or bundled stabilized microtubules blocks. When overexpressed, inhibits mitotic spindle assembly and nuclear envelope breakdown, apparently without affecting other cellular events.,PTM:Phosphorylated by TPK II. Poor substrate for GSK3.,similarity:Belongs to the TPPP family.,subunit:May form dimers. Binds tubulin; binding is inhibited by GTP. Interacts with GSK3.,tissue specificity:Widely expressed.,
  • 細(xì)胞定位： Golgi outpost . Cytoplasm, cytoskeleton, microtubule organizing center . Cytoplasm, cytoskeleton . Nucleus . Cytoplasm, cytoskeleton, spindle . Specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, which shapes dendrite morphology by functioning as sites of acentrosomal microtubule nucleation (By similarity). Mainly localizes to the cytoskeleton (PubMed:18028908). Also found in the nucleus; however, nuclear localization is unclear and requires additional evidences (PubMed:18028908). Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies (PubMed:15590652, PubMed:17027006). During mitosis, colocalizes with LIMK2 at the mitotic spindle (PubMed:22328514). .
  • 組織表達： Widely expressed.
  • 科研貨號： PLA021474
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