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TRF2 rabbit pAb
商品貨號(hào)： PLA021473
適 應(yīng) 性： 人,小鼠,大鼠
WB
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： TERF2 TRBF2 TRF2
  • 蛋白名稱： TRF2
  • Human_gene_id： 7014
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7014
  • Human_swiss_prot_no： Q15554
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q15554/entry
  • Mouse_gene_id： 21750
  • Mouse_gene_link： https://www.uniprot.org/uniprot/21750
  • Mouse_swiss_prot_no： O35144
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35144
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of TRF2 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
  • 分子量： 55kD
  • 功能： function:Binds the telomeric double-stranded TTAGGG repeat. Protects against end-to-end fusion of chromosomes and plays a role in successful progression through the cell division cycle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HTH myb-type DNA-binding domain.,subcellular location:Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.,subunit:Homodimer. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Binds to RAP1. Interacts with NBN.,tissue specificity:Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.,
  • 細(xì)胞定位： Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.
  • 組織表達(dá)： Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.
  • 科研貨號(hào)： PLA021473
TRF2 rabbit pAb
Catalog No PLA021473
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： TERF2 TRBF2 TRF2
  • 蛋白名稱： TRF2
  • Human_gene_id： 7014
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7014
  • Human_swiss_prot_no： Q15554
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q15554/entry
  • Mouse_gene_id： 21750
  • Mouse_gene_link： https://www.uniprot.org/uniprot/21750
  • Mouse_swiss_prot_no： O35144
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O35144
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of TRF2 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
  • 分子量： 55kD
  • 功能： function:Binds the telomeric double-stranded TTAGGG repeat. Protects against end-to-end fusion of chromosomes and plays a role in successful progression through the cell division cycle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 HTH myb-type DNA-binding domain.,subcellular location:Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.,subunit:Homodimer. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Binds to RAP1. Interacts with NBN.,tissue specificity:Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.,
  • 細(xì)胞定位： Nucleus . Chromosome, telomere . Colocalizes with telomeric DNA in interphase cells and is located at chromosome ends during metaphase.
  • 組織表達(dá)： Ubiquitous. Highly expressed in spleen, thymus, prostate, uterus, testis, small intestine, colon and peripheral blood leukocytes.
  • 科研貨號(hào)： PLA021473
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hnntwy.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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