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HIPK1/2/3 rabbit pAb
商品貨號： PLA021470
適 應 性： 人,小鼠,大鼠
WB
￥600元
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： HIPK1 KIAA0630 MYAK NBAK2
  • 蛋白名稱： HIPK1/2/3
  • Human_gene_id： 204851
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=204851
  • Human_swiss_prot_no： Q86Z02
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86Z02/entry
  • Mouse_gene_id： 15257
  • Mouse_gene_link： https://www.uniprot.org/uniprot/15257
  • Mouse_swiss_prot_no： O88904
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O88904
  • Rat_swiss_prot_no： A4L9P5
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/A4L9P5
  • 特異性： This antibody detects endogenous levels of HIPK1/2/3 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)
  • 分子量： 133kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.,PTM:Autophosphorylated. Phosphorylated and activated by JNK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly nuclear.,subunit:Interacts with Nkx1-2 and Nkx2-5 (By similarity). Interacts with DAXX and TP53.,tissue specificity:Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.,
  • 細胞定位： Nucleus . Cytoplasm . Nucleus speckle . Predominantly nuclear. Translocates from nucleus to cytoplasm in response to stress stimuli via SENP1-mediated desumoylation. .
  • 組織表達： Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines. Isoform 2 is highly expressed in testis. Expressed in both androgen-dependent and androgen-independent prostate cancer cells (PubMed:28289210).
  • 科研貨號： PLA021470
HIPK1/2/3 rabbit pAb
Catalog No PLA021470
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： HIPK1 KIAA0630 MYAK NBAK2
  • 蛋白名稱： HIPK1/2/3
  • Human_gene_id： 204851
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=204851
  • Human_swiss_prot_no： Q86Z02
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q86Z02/entry
  • Mouse_gene_id： 15257
  • Mouse_gene_link： https://www.uniprot.org/uniprot/15257
  • Mouse_swiss_prot_no： O88904
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O88904
  • Rat_swiss_prot_no： A4L9P5
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/A4L9P5
  • 特異性： This antibody detects endogenous levels of HIPK1/2/3 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Homeodomain-interacting protein kinase 1 (EC 2.7.11.1) (Nuclear body-associated kinase 2)
  • 分子量： 133kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May play a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. May be involved in malignant squamous cell tumor formation.,PTM:Autophosphorylated. Phosphorylated and activated by JNK1.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly nuclear.,subunit:Interacts with Nkx1-2 and Nkx2-5 (By similarity). Interacts with DAXX and TP53.,tissue specificity:Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines.,
  • 細胞定位： Nucleus . Cytoplasm . Nucleus speckle . Predominantly nuclear. Translocates from nucleus to cytoplasm in response to stress stimuli via SENP1-mediated desumoylation. .
  • 組織表達： Ubiquitously expressed with highest levels in skeletal muscle and heart. Overexpressed in breast cancer cell lines. Isoform 2 is highly expressed in testis. Expressed in both androgen-dependent and androgen-independent prostate cancer cells (PubMed:28289210).
  • 科研貨號： PLA021470
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