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DYRK2/4 rabbit pAb
商品貨號(hào)： PLA021467
適 應(yīng) 性： 人,小鼠,大鼠
WB
￥600元
規(guī)格：
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MSDS
說(shuō)明書(shū)
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： DYRK2
  • 蛋白名稱： DYRK2/4
  • Human_gene_id： 8445
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8445
  • Human_swiss_prot_no： Q92630
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q92630/entry
  • Mouse_gene_id： 69181
  • Mouse_gene_link： https://www.uniprot.org/uniprot/69181
  • Mouse_swiss_prot_no： Q5U4C9
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q5U4C9
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of DYRK2/4 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
  • 分子量： 66kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,cofactor:Manganese.,enzyme regulation:Autophosphorylates on tyrosine residues.,function:Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates.,PTM:Phosphorylated on serine/threonine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Translocates into the nucleus following DNA damage.,tissue specificity:Testis, after the onset of spermatogenesis.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3510
  • 細(xì)胞定位： Cytoplasm. Nucleus. Translocates into the nucleus following DNA damage.
  • 組織表達(dá)： Testis, after the onset of spermatogenesis.
  • 科研貨號(hào)： PLA021467
DYRK2/4 rabbit pAb
Catalog No PLA021467
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： DYRK2
  • 蛋白名稱： DYRK2/4
  • Human_gene_id： 8445
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=8445
  • Human_swiss_prot_no： Q92630
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q92630/entry
  • Mouse_gene_id： 69181
  • Mouse_gene_link： https://www.uniprot.org/uniprot/69181
  • Mouse_swiss_prot_no： Q5U4C9
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q5U4C9
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/0
  • 特異性： This antibody detects endogenous levels of DYRK2/4 at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Dual specificity tyrosine-phosphorylation-regulated kinase 2 (EC 2.7.12.1)
  • 分子量： 66kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,cofactor:Manganese.,enzyme regulation:Autophosphorylates on tyrosine residues.,function:Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates.,PTM:Phosphorylated on serine/threonine residues.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Translocates into the nucleus following DNA damage.,tissue specificity:Testis, after the onset of spermatogenesis.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3510
  • 細(xì)胞定位： Cytoplasm. Nucleus. Translocates into the nucleus following DNA damage.
  • 組織表達(dá)： Testis, after the onset of spermatogenesis.
  • 科研貨號(hào)： PLA021467
    • Hunan UPT Biotechnology Co.,Ltd
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    E-mail：service@uptbio.com
    Address：
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