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p38-γ/δ rabbit pAb
商品貨號： PLA021460
適 應(yīng) 性： 人,小鼠,大鼠
WB
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： MAPK12 ERK6 SAPK3
  • 蛋白名稱： p38-γ/δ
  • Human_gene_id： 6300
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6300
  • Human_swiss_prot_no： P53778
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P53778/entry
  • Mouse_gene_id： 29857
  • Mouse_gene_link： https://www.uniprot.org/uniprot/29857
  • Mouse_swiss_prot_no： O08911
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O08911
  • Rat_gene_id： 60352
  • Rat_gene_link： https://www.uniprot.org/uniprot/60352
  • Rat_swiss_prot_no： Q63538
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q63538
  • 特異性： This antibody detects endogenous levels of p38-γ/δ at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)
  • 分子量： 40kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Binds 2 magnesium ions.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by phosphorylation on threonine and tyrosine.,function:Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.,PTM:Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Mitochondrial when associated with SH3BP5.,subunit:Monomer. Interacts with the PDZ domain of the syntrophin SNTA1. Interacts with SH3BP5.,tissue specificity:Highly expressed in skeletal muscle and heart.,
  • 細(xì)胞定位： Cytoplasm. Nucleus. Mitochondrion. Mitochondrial when associated with SH3BP5. In skeletal muscle colocalizes with SNTA1 at the neuromuscular junction and throughout the sarcolemma (By similarity). .
  • 組織表達(dá)： Highly expressed in skeletal muscle and heart.
  • 科研貨號： PLA021460
p38-γ/δ rabbit pAb
Catalog No PLA021460
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： MAPK12 ERK6 SAPK3
  • 蛋白名稱： p38-γ/δ
  • Human_gene_id： 6300
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6300
  • Human_swiss_prot_no： P53778
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P53778/entry
  • Mouse_gene_id： 29857
  • Mouse_gene_link： https://www.uniprot.org/uniprot/29857
  • Mouse_swiss_prot_no： O08911
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/O08911
  • Rat_gene_id： 60352
  • Rat_gene_link： https://www.uniprot.org/uniprot/60352
  • Rat_swiss_prot_no： Q63538
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q63538
  • 特異性： This antibody detects endogenous levels of p38-γ/δ at Human, Mouse,Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Mitogen-activated protein kinase 12 (MAP kinase 12) (MAPK 12) (EC 2.7.11.24) (Extracellular signal-regulated kinase 6) (ERK-6) (Mitogen-activated protein kinase p38 gamma) (MAP kinase p38 gamma) (Stress-activated protein kinase 3)
  • 分子量： 40kD
  • 功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Binds 2 magnesium ions.,domain:The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.,enzyme regulation:Activated by phosphorylation on threonine and tyrosine.,function:Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating downstream targets. Plays a role in myoblast differentiation and also in the down-regulation of cyclin D1 in response to hypoxia in adrenal cells suggesting MAPK12 may inhibit cell proliferation while promoting differentiation.,PTM:Dually phosphorylated on Thr-183 and Tyr-185, which activates the enzyme.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Mitochondrial when associated with SH3BP5.,subunit:Monomer. Interacts with the PDZ domain of the syntrophin SNTA1. Interacts with SH3BP5.,tissue specificity:Highly expressed in skeletal muscle and heart.,
  • 細(xì)胞定位： Cytoplasm. Nucleus. Mitochondrion. Mitochondrial when associated with SH3BP5. In skeletal muscle colocalizes with SNTA1 at the neuromuscular junction and throughout the sarcolemma (By similarity). .
  • 組織表達(dá)： Highly expressed in skeletal muscle and heart.
  • 科研貨號： PLA021460
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