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Prealbumin rabbit pAb
商品貨號(hào)： PLA021349
適 應(yīng) 性： 人,大鼠,小鼠,
WB IHC
￥600元
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MSDS
說(shuō)明書(shū)
商品描述
  • 基因名稱(chēng)： TTR PALB
  • 蛋白名稱(chēng)： Prealbumin
  • Human_gene_id： 7276
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7276
  • Human_swiss_prot_no： P02766
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P02766/entry
  • Mouse_gene_id： 22139
  • Mouse_gene_link： https://www.uniprot.org/uniprot/22139
  • Mouse_swiss_prot_no： P07309
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P07309
  • Rat_gene_id： 24856
  • Rat_gene_link： https://www.uniprot.org/uniprot/24856
  • Rat_swiss_prot_no： P02767
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P02767
  • 特異性： This antibody detects endogenous levels of Human Prealbumin
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱(chēng)： Transthyretin (ATTR;Prealbumin;TBPA)
  • 分子量： 16kD
  • 功能： disease:Defects in TTR are a cause of hyperthyroxinemia [MIM:176300].,disease:Defects in TTR are the cause of amyloidosis type 1 (AMYL1) [MIM:176300]. AMYL1 is a hereditary generalized amyloidosis due to transthyretin amyloid deposition. Protein fibrils can form in different tissues leading to amyloid polyneuropathies, amyloidotic cardiomyopathy, carpal tunnel syndrome, systemic senile amyloidosis.,disease:Defects in TTR are the cause of amyloidosis type 7 (AMYL7) [MIM:105210]; also known as leptomeningeal amyloidosis or meningocerebrovascular amyloidosis. AMYL7 is a form of hereditary transthyretin amyloidosis characterized by primary involvement of the central nervous system. Neuropathologic examination shows amyloid in the walls of leptomeningeal vessels, in pia arachnoid, and subpial deposits. Some patients also develop vitreous amyloid deposition that leads to visual impairment (oculoleptomeningeal amyloidosis). Clinical features include seizures, stroke-like episodes, dementia, psychomotor deterioration, variable amyloid deposition in the vitreous humor. Mild systemic amyloidosis may occurr.,domain:Each monomer has two 4-stranded beta sheets and the shape of a prolate ellipsoid. Antiparallel beta-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex beta-sheets of the dimers to form an internal channel.,function:Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.,miscellaneous:About 40% of plasma transthyretin circulates in a tight protein-protein complex with the plasma retinol-binding protein (RBP). The formation of the complex with RBP stabilizes the binding of retinol to RBP and decreases the glomerular filtration and renal catabolism of the relatively small RBP molecule. There is evidence for 2 binding sites for RBP, one possibly being a region that includes Ile-104, located on the outer surface of the transthyretin molecule.,miscellaneous:Two binding sites for thyroxine are located in the channel. Less than 1% of plasma prealbumin molecules are normally involved in thyroxine transport. L-thyroxine binds to the transthyretin by an order of magnitude stronger than does the triiodo-L-thyronine. Thyroxine-binding globulin is the major carrier protein for thyroid hormones in man.,online information:Transthyretin entry,similarity:Belongs to the transthyretin family.,subunit:Homotetramer.,tissue specificity:Most abundant in the choroid plexus. Also present in the liver.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3366
  • 細(xì)胞定位： Secreted. Cytoplasm.
  • 組織表達(dá)： Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.
  • 科研貨號(hào)： PLA021349
Prealbumin rabbit pAb
Catalog No PLA021349
Product information
  • 基因名稱(chēng)： TTR PALB
  • 蛋白名稱(chēng)： Prealbumin
  • Human_gene_id： 7276
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7276
  • Human_swiss_prot_no： P02766
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P02766/entry
  • Mouse_gene_id： 22139
  • Mouse_gene_link： https://www.uniprot.org/uniprot/22139
  • Mouse_swiss_prot_no： P07309
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/P07309
  • Rat_gene_id： 24856
  • Rat_gene_link： https://www.uniprot.org/uniprot/24856
  • Rat_swiss_prot_no： P02767
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/P02767
  • 特異性： This antibody detects endogenous levels of Human Prealbumin
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1:500-2000;IHC-p 1:50-300
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱(chēng)： Transthyretin (ATTR;Prealbumin;TBPA)
  • 分子量： 16kD
  • 功能： disease:Defects in TTR are a cause of hyperthyroxinemia [MIM:176300].,disease:Defects in TTR are the cause of amyloidosis type 1 (AMYL1) [MIM:176300]. AMYL1 is a hereditary generalized amyloidosis due to transthyretin amyloid deposition. Protein fibrils can form in different tissues leading to amyloid polyneuropathies, amyloidotic cardiomyopathy, carpal tunnel syndrome, systemic senile amyloidosis.,disease:Defects in TTR are the cause of amyloidosis type 7 (AMYL7) [MIM:105210]; also known as leptomeningeal amyloidosis or meningocerebrovascular amyloidosis. AMYL7 is a form of hereditary transthyretin amyloidosis characterized by primary involvement of the central nervous system. Neuropathologic examination shows amyloid in the walls of leptomeningeal vessels, in pia arachnoid, and subpial deposits. Some patients also develop vitreous amyloid deposition that leads to visual impairment (oculoleptomeningeal amyloidosis). Clinical features include seizures, stroke-like episodes, dementia, psychomotor deterioration, variable amyloid deposition in the vitreous humor. Mild systemic amyloidosis may occurr.,domain:Each monomer has two 4-stranded beta sheets and the shape of a prolate ellipsoid. Antiparallel beta-sheet interactions link monomers into dimers. A short loop from each monomer forms the main dimer-dimer interaction. These two pairs of loops separate the opposed, convex beta-sheets of the dimers to form an internal channel.,function:Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.,miscellaneous:About 40% of plasma transthyretin circulates in a tight protein-protein complex with the plasma retinol-binding protein (RBP). The formation of the complex with RBP stabilizes the binding of retinol to RBP and decreases the glomerular filtration and renal catabolism of the relatively small RBP molecule. There is evidence for 2 binding sites for RBP, one possibly being a region that includes Ile-104, located on the outer surface of the transthyretin molecule.,miscellaneous:Two binding sites for thyroxine are located in the channel. Less than 1% of plasma prealbumin molecules are normally involved in thyroxine transport. L-thyroxine binds to the transthyretin by an order of magnitude stronger than does the triiodo-L-thyronine. Thyroxine-binding globulin is the major carrier protein for thyroid hormones in man.,online information:Transthyretin entry,similarity:Belongs to the transthyretin family.,subunit:Homotetramer.,tissue specificity:Most abundant in the choroid plexus. Also present in the liver.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3366
  • 細(xì)胞定位： Secreted. Cytoplasm.
  • 組織表達(dá)： Detected in serum and cerebrospinal fluid (at protein level). Highly expressed in choroid plexus epithelial cells. Detected in retina pigment epithelium and liver.
  • 科研貨號(hào)： PLA021349
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