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APOA rabbit pAb
商品貨號： PLA021313
適 應(yīng) 性： 人,大鼠,小鼠,
WB ELISA
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： LPA
  • 蛋白名稱： APOA
  • Human_gene_id： 4018
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4018
  • Human_swiss_prot_no： P08519
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P08519/entry
  • 特異性： This antibody detects endogenous levels of Human APOA
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Apolipoprotein(a;Apo(a);Lp(a);EC 3.4.21.-)
  • 分子量： 500kD
  • 功能： disease:Elevated plasma concentrations of apo(a) and its naturally occurring proteolytic fragments are correlated with atherosclerosis. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.,function:Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.,miscellaneous:Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation.,online information:The Singapore human mutation and polymorphism database,polymorphism:The genome version encodes a variant that contains 16 Kringle domains and that lack residues 533 to 3040.,PTM:N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 38 kringle domains.,subunit:Disulfide-linked to apo-B100. Binds to fibronectin and decorin.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3327
  • 科研貨號： PLA021313
APOA rabbit pAb
Catalog No PLA021313
Product information
  • 基因名稱： LPA
  • 蛋白名稱： APOA
  • Human_gene_id： 4018
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4018
  • Human_swiss_prot_no： P08519
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P08519/entry
  • 特異性： This antibody detects endogenous levels of Human APOA
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Apolipoprotein(a;Apo(a);Lp(a);EC 3.4.21.-)
  • 分子量： 500kD
  • 功能： disease:Elevated plasma concentrations of apo(a) and its naturally occurring proteolytic fragments are correlated with atherosclerosis. Homology with plasminogen kringles IV and V is thought to underlie the atherogenicity of the protein, because the fragments are competing with plasminogen for fibrin(ogen) binding.,function:Apo(a) is the main constituent of lipoprotein(a) (Lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1. Lp(a) may be a ligand for megalin/Gp 330.,miscellaneous:Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-Lp(a). Apo(a) fragments accumulate in atherosclerotic lesions, where they may promote thrombogenesis. O-glycosylation may limit the extent of proteolytic fragmentation.,online information:The Singapore human mutation and polymorphism database,polymorphism:The genome version encodes a variant that contains 16 Kringle domains and that lack residues 533 to 3040.,PTM:N- and O-glycosylated. The N-glycans are complex biantennary structures present in either a mono- or disialylated state. The O-glycans are mostly (80%) represented by the monosialylated core type I structure, NeuNAcalpha2-3Galbeta1-3GalNAc, with smaller amounts of disialylated and non-sialylated O-glycans also detected.,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Plasminogen subfamily.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 38 kringle domains.,subunit:Disulfide-linked to apo-B100. Binds to fibronectin and decorin.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3327
  • 科研貨號： PLA021313
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