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CIB1 rabbit pAb
商品貨號(hào)： PLA021285
適 應(yīng) 性： 人,大鼠,小鼠,
WB ELISA
￥600元
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MSDS
說明書
商品描述
  • 基因名稱： CIB1 CIB KIP PRKDCIP
  • 蛋白名稱： CIB1
  • Human_gene_id： 10519
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10519
  • Human_swiss_prot_no： Q99828
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q99828/entry
  • Mouse_gene_id： 23991
  • Mouse_gene_link： https://www.uniprot.org/uniprot/23991
  • Mouse_swiss_prot_no： Q9Z0F4
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z0F4
  • Rat_gene_id： 81823
  • Rat_gene_link： https://www.uniprot.org/uniprot/81823
  • Rat_swiss_prot_no： Q9R010
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q9R010
  • 特異性： This antibody detects endogenous levels of Human CIB1
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Calcium and integrin-binding protein 1 (CIB;Calcium- and integrin-binding protein;CIBP;Calmyrin;DNA-PKcs-interacting protein;Kinase-interacting protein;KIP;SNK-interacting protein 2-28;SIP2-28)
  • 分子量： 21kD
  • 功能： function:May convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through the binding to the integrin cytoplasmic domain.,similarity:Contains 2 EF-hand domains.,subunit:Monomer. Interacts with the heterodimeric integrin alpha-IIb/beta3. Interacts with the protein kinases PLK2/SNK and with the region immediately upstream of the kinase domain of DNA-PK. Interacts with PSEN2. Interacts with MYO1C.,tissue specificity:Ubiquitous.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3298
  • 細(xì)胞定位： Membrane; Lipid-anchor. Cell membrane, sarcolemma. Cell membrane. Apical cell membrane. Cell projection, ruffle membrane. Cell projection, filopodium tip. Cell projection, growth cone . Cell projection, lamellipodium . Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Nucleus . Cell projection, neuron projection . Perikaryon . Colocalized with PPP3R1 at the cell membrane of cardiomyocytes in the hypertrophic heart (By similarity). Colocalized with NBR1 to the perinuclear region. Colocalizes with TAS1R2 in apical regions of taste receptor cells. Colocalized with RAC3 in the perinuclear area and at the cell periphery. Colocalized with PAK1 within membrane ruffles during cell spreading upon readhesion to fibronectin. Redistributed to the cytoskeleton upon platelet aggregation. Translocates from the cytosol to the plasma membrane in a calcium-dependent manner. Colocalized with PLK3 at centrosomes in ductal breast carcinoma cells. .; [Isoform 2]: Cytoplasm, perinuclear region . Golgi apparatus, trans-Golgi network .
  • 組織表達(dá)： Ubiquitously expressed. Expressed in the epidermis, hair follicles and keratinocytes (PubMed:30068544). Detected in platelets and in cell lines of megakaryocytic and erythrocytic lineages. Both isoform 1 and isoform 2 are detected in various cancer cell lines, with isoform 2 being the predominant form (at protein level).
  • 科研貨號(hào)： PLA021285
CIB1 rabbit pAb
Catalog No PLA021285
Product information
  • 基因名稱： CIB1 CIB KIP PRKDCIP
  • 蛋白名稱： CIB1
  • Human_gene_id： 10519
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10519
  • Human_swiss_prot_no： Q99828
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q99828/entry
  • Mouse_gene_id： 23991
  • Mouse_gene_link： https://www.uniprot.org/uniprot/23991
  • Mouse_swiss_prot_no： Q9Z0F4
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9Z0F4
  • Rat_gene_id： 81823
  • Rat_gene_link： https://www.uniprot.org/uniprot/81823
  • Rat_swiss_prot_no： Q9R010
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q9R010
  • 特異性： This antibody detects endogenous levels of Human CIB1
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:1000-2000 ELISA 1:5000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 其他名稱： Calcium and integrin-binding protein 1 (CIB;Calcium- and integrin-binding protein;CIBP;Calmyrin;DNA-PKcs-interacting protein;Kinase-interacting protein;KIP;SNK-interacting protein 2-28;SIP2-28)
  • 分子量： 21kD
  • 功能： function:May convert the inactive conformation of integrin alpha-IIb/beta3 to an active form through the binding to the integrin cytoplasmic domain.,similarity:Contains 2 EF-hand domains.,subunit:Monomer. Interacts with the heterodimeric integrin alpha-IIb/beta3. Interacts with the protein kinases PLK2/SNK and with the region immediately upstream of the kinase domain of DNA-PK. Interacts with PSEN2. Interacts with MYO1C.,tissue specificity:Ubiquitous.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3298
  • 細(xì)胞定位： Membrane; Lipid-anchor. Cell membrane, sarcolemma. Cell membrane. Apical cell membrane. Cell projection, ruffle membrane. Cell projection, filopodium tip. Cell projection, growth cone . Cell projection, lamellipodium . Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, perinuclear region. Nucleus . Cell projection, neuron projection . Perikaryon . Colocalized with PPP3R1 at the cell membrane of cardiomyocytes in the hypertrophic heart (By similarity). Colocalized with NBR1 to the perinuclear region. Colocalizes with TAS1R2 in apical regions of taste receptor cells. Colocalized with RAC3 in the perinuclear area and at the cell periphery. Colocalized with PAK1 within membrane ruffles during cell spreading upon readhesion to fibronectin. Redistributed to the cytoskeleton upon platelet aggregation. Translocates from the cytosol to the plasma membrane in a calcium-dependent manner. Colocalized with PLK3 at centrosomes in ductal breast carcinoma cells. .; [Isoform 2]: Cytoplasm, perinuclear region . Golgi apparatus, trans-Golgi network .
  • 組織表達(dá)： Ubiquitously expressed. Expressed in the epidermis, hair follicles and keratinocytes (PubMed:30068544). Detected in platelets and in cell lines of megakaryocytic and erythrocytic lineages. Both isoform 1 and isoform 2 are detected in various cancer cell lines, with isoform 2 being the predominant form (at protein level).
  • 科研貨號(hào)： PLA021285
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