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FANCB rabbit pAb
商品貨號(hào)： PLA021054
適 應(yīng) 性： 人,小鼠
WB
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： FANCB
  • 蛋白名稱： FANCB
  • Human_gene_id： 2187
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2187
  • Human_swiss_prot_no： Q8NB91
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8NB91/entry
  • Mouse_gene_id： 237211
  • Mouse_gene_link： https://www.uniprot.org/uniprot/237211
  • Mouse_swiss_prot_no： Q5XJY6
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q5XJY6
  • 特異性： This antibody detects endogenous levels of FANCB at Human/Mouse
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 94kD
  • 功能： disease:Defects in FANCB are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.,disease:Defects in FANCB are the cause of cause of Fanconi anemia complementation group B (FANCB) [MIM:300514]; also called Fanconi pancytopenia type 2 (FA2).,disease:Defects in FANCB are the cause of X-linked VACTERL-H (XVACTERL-H) [MIM:314390]; also known as X-linked VACTERL association with hydrocephalus syndrome. VACTERL is an acronym for vertebral anomalies, anal atresia, cardiac malformations, tracheoesophageal fistula, renal anomalies (urethral atresia with hydronephrosis), and limb anomalies (hexadactyly, humeral hypoplasia, radial aplasia, and proximally placed thumb). Some cases of VACTERL-H are associated with increased chromosome breakage and rearrangement.,function:DNA repair protein required for FANCD2 ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 科研貨號(hào)： PLA021054
FANCB rabbit pAb
Catalog No PLA021054
Product information
  • 基因名稱： FANCB
  • 蛋白名稱： FANCB
  • Human_gene_id： 2187
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=2187
  • Human_swiss_prot_no： Q8NB91
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q8NB91/entry
  • Mouse_gene_id： 237211
  • Mouse_gene_link： https://www.uniprot.org/uniprot/237211
  • Mouse_swiss_prot_no： Q5XJY6
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q5XJY6
  • 特異性： This antibody detects endogenous levels of FANCB at Human/Mouse
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 94kD
  • 功能： disease:Defects in FANCB are a cause of Fanconi anemia (FA) [MIM:227650]. FA is a genetically heterogeneous, autosomal recessive disorder characterized by progressive pancytopenia, a diverse assortment of congenital malformations, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair.,disease:Defects in FANCB are the cause of cause of Fanconi anemia complementation group B (FANCB) [MIM:300514]; also called Fanconi pancytopenia type 2 (FA2).,disease:Defects in FANCB are the cause of X-linked VACTERL-H (XVACTERL-H) [MIM:314390]; also known as X-linked VACTERL association with hydrocephalus syndrome. VACTERL is an acronym for vertebral anomalies, anal atresia, cardiac malformations, tracheoesophageal fistula, renal anomalies (urethral atresia with hydronephrosis), and limb anomalies (hexadactyly, humeral hypoplasia, radial aplasia, and proximally placed thumb). Some cases of VACTERL-H are associated with increased chromosome breakage and rearrangement.,function:DNA repair protein required for FANCD2 ubiquitination.,sequence caution:Contaminating sequence. Potential poly-A sequence.,subunit:Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. The complex is not found in FA patients.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 科研貨號(hào)： PLA021054
    • Hunan UPT Biotechnology Co.,Ltd
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