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DU4L7 rabbit pAb
商品貨號： PLA020972
適 應(yīng) 性： 人,大鼠,小鼠,
WB
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： DUX4L7
  • 蛋白名稱： DU4L7
  • Human_swiss_prot_no： P0CJ90
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P0CJ90/entry
  • 特異性： This antibody detects endogenous levels of DU4L7 at Human
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 47kD
  • 功能： disease:Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD) [MIM:158900]. FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.,domain:Both homebox domains confer nuclear targeting.,function:May be involved in transcriptional regulation.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes.,similarity:Belongs to the paired homeobox family.,similarity:Contains 2 homeobox DNA-binding domains.,subcellular location:Actively transported through the nuclear pore complex (NPC).,subunit:May exist as a monomer or a dimer.,tissue specificity:Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 科研貨號： PLA020972
DU4L7 rabbit pAb
Catalog No PLA020972
Product information
  • 基因名稱： DUX4L7
  • 蛋白名稱： DU4L7
  • Human_swiss_prot_no： P0CJ90
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/P0CJ90/entry
  • 特異性： This antibody detects endogenous levels of DU4L7 at Human
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 47kD
  • 功能： disease:Defects in DUX4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD) [MIM:158900]. FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Severity is highly variable. Weakness is slowly progressive and about 20% of affected individuals eventually require a wheelchair. Approximately 70-90% of individuals have inherited the disease-causing deletion from a parent, and approximately 10-30% of affected individuals have FSHD as the result of a de novo deletion. Offsprings of an affected individual have a 50% chance of inheriting the deletion.,domain:Both homebox domains confer nuclear targeting.,function:May be involved in transcriptional regulation.,miscellaneous:DUX genes are present in 3.3-kilobase elements, a tandem repeat family scattered in the genome found on the short arms of all acrocentric chromosomes as well as on several other chromosomes.,similarity:Belongs to the paired homeobox family.,similarity:Contains 2 homeobox DNA-binding domains.,subcellular location:Actively transported through the nuclear pore complex (NPC).,subunit:May exist as a monomer or a dimer.,tissue specificity:Does not seem to be expressed in normal muscle, but in muscle of individuals with FSHD, where it may be toxic to cells.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Nucleus .
  • 科研貨號： PLA020972
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