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AT132 rabbit pAb
商品貨號(hào)： PLA020964
適 應(yīng) 性： 人,小鼠
WB
￥600元
規(guī)格：
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MSDS
說(shuō)明書(shū)
商品描述
  • 基因名稱(chēng)： ATP13A2 PARK9
  • 蛋白名稱(chēng)： AT132
  • Human_gene_id： 23400
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23400
  • Human_swiss_prot_no： Q9NQ11
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NQ11/entry
  • Mouse_gene_id： 74772
  • Mouse_gene_link： https://www.uniprot.org/uniprot/74772
  • Mouse_swiss_prot_no： Q9CTG6
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9CTG6
  • 特異性： This antibody detects endogenous levels of AT132 at Human/Mouse
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 130kD
  • 功能： catalytic activity:ATP + H(2)O = ADP + phosphate.,disease:Defects in ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS) [MIM:606693]; also known as Parkinson disease-9. KRS is a rare hereditary disease with juvenile onset. In addition to typical signs of Parkinson disease, affected individuals show symptoms of more widespread neurodegeneration, including dementia.,similarity:Belongs to the cation transport ATPase (P-type) family.,similarity:Belongs to the cation transport ATPase (P-type) family. Type V subfamily.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Lysosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endosome, multivesicular body membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein .
  • 組織表達(dá)： Expressed in brain; protein levels are markedly increased in brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout the cingulate cortex (at protein level). In the substantia nigra, it is found in neuromelanin-positive dopaminergic neurons (at protein level).
  • 科研貨號(hào)： PLA020964
AT132 rabbit pAb
Catalog No PLA020964
Product information
  • 基因名稱(chēng)： ATP13A2 PARK9
  • 蛋白名稱(chēng)： AT132
  • Human_gene_id： 23400
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=23400
  • Human_swiss_prot_no： Q9NQ11
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9NQ11/entry
  • Mouse_gene_id： 74772
  • Mouse_gene_link： https://www.uniprot.org/uniprot/74772
  • Mouse_swiss_prot_no： Q9CTG6
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q9CTG6
  • 特異性： This antibody detects endogenous levels of AT132 at Human/Mouse
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來(lái)源： Polyclonal, Rabbit,IgG
  • 稀釋?zhuān)? WB 1：500-2000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說(shuō)明書(shū)： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 130kD
  • 功能： catalytic activity:ATP + H(2)O = ADP + phosphate.,disease:Defects in ATP13A2 are the cause of Kufor-Rakeb syndrome (KRS) [MIM:606693]; also known as Parkinson disease-9. KRS is a rare hereditary disease with juvenile onset. In addition to typical signs of Parkinson disease, affected individuals show symptoms of more widespread neurodegeneration, including dementia.,similarity:Belongs to the cation transport ATPase (P-type) family.,similarity:Belongs to the cation transport ATPase (P-type) family. Type V subfamily.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Lysosome membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Endosome, multivesicular body membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein .
  • 組織表達(dá)： Expressed in brain; protein levels are markedly increased in brain from subjects with Parkinson disease and subjects with dementia with Lewy bodies. Detected in pyramidal neurons located throughout the cingulate cortex (at protein level). In the substantia nigra, it is found in neuromelanin-positive dopaminergic neurons (at protein level).
  • 科研貨號(hào)： PLA020964
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