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SIN1 rabbit pAb
商品貨號(hào)： PLA020757
適 應(yīng) 性： 人,小鼠,大鼠
WB IHC ELISA
￥600元
規(guī)格：
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MSDS
說明書
商品描述
  • 基因名稱： MAPKAP1 MIP1 SIN1
  • 蛋白名稱： SIN1
  • Human_gene_id： 79109
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79109
  • Human_swiss_prot_no： Q9BPZ7
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9BPZ7/entry
  • Mouse_gene_id： 227743
  • Mouse_gene_link： https://www.uniprot.org/uniprot/227743
  • Mouse_swiss_prot_no： Q8BKH7
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BKH7
  • Rat_gene_id： 296648
  • Rat_gene_link： https://www.uniprot.org/uniprot/296648
  • Rat_swiss_prot_no： Q6AYF1
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6AYF1
  • 特異性： This antibody detects endogenous levels of SIN1 at Human/Mouse/Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 57kD
  • 功能： function:Essential component of the TORC2 complex, which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. Inhibits MAP3K2 by preventing its dimerization and autophosphorylation. Inhibits HRAS and KRAs signaling. Enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription.,similarity:Belongs to the SIN1 family.,subunit:All isoforms except isoform 4 are able to be part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. Interacts with ATF2, MAP3K2 and MAPK8. Interacts with GTP-bound HRAS and KRAS. Interacts with IFNAR2.,tissue specificity:Ubiquitously expressed, with highest levels in heart and skeletal muscle.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle. Nucleus.
  • 組織表達(dá)： Ubiquitously expressed, with highest levels in heart and skeletal muscle.
  • 科研貨號(hào)： PLA020757
SIN1 rabbit pAb
Catalog No PLA020757
Product information
  • 基因名稱： MAPKAP1 MIP1 SIN1
  • 蛋白名稱： SIN1
  • Human_gene_id： 79109
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=79109
  • Human_swiss_prot_no： Q9BPZ7
  • Human_swiss_link： https://www.uniprot.org/uniprotkb/Q9BPZ7/entry
  • Mouse_gene_id： 227743
  • Mouse_gene_link： https://www.uniprot.org/uniprot/227743
  • Mouse_swiss_prot_no： Q8BKH7
  • Mouse_swiss_link： https://www.uniprot.org/uniprotkb/Q8BKH7
  • Rat_gene_id： 296648
  • Rat_gene_link： https://www.uniprot.org/uniprot/296648
  • Rat_swiss_prot_no： Q6AYF1
  • Rat_swiss_link： https://www.uniprot.org/uniprotkb/Q6AYF1
  • 特異性： This antibody detects endogenous levels of SIN1 at Human/Mouse/Rat
  • 組成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 來源： Polyclonal, Rabbit,IgG
  • 稀釋： WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 純化工藝： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度： 1 mg/ml
  • 儲(chǔ)存： -15°C to -25°C/1 year(Do not lower than -25°C)
  • 說明書： 1
  • Msds： MSDS_Antibody.pdf
  • 分子量： 57kD
  • 功能： function:Essential component of the TORC2 complex, which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization. Inhibits MAP3K2 by preventing its dimerization and autophosphorylation. Inhibits HRAS and KRAs signaling. Enhances osmotic stress-induced phosphorylation of ATF2 and ATF2-mediated transcription.,similarity:Belongs to the SIN1 family.,subunit:All isoforms except isoform 4 are able to be part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. Interacts with ATF2, MAP3K2 and MAPK8. Interacts with GTP-bound HRAS and KRAS. Interacts with IFNAR2.,tissue specificity:Ubiquitously expressed, with highest levels in heart and skeletal muscle.,
  • 相關(guān)產(chǎn)品： RS0001,RS0002,YM3028,YM3029
  • 細(xì)胞定位： Cell membrane; Peripheral membrane protein. Cytoplasmic vesicle. Nucleus.
  • 組織表達(dá)： Ubiquitously expressed, with highest levels in heart and skeletal muscle.
  • 科研貨號(hào)： PLA020757
    • Hunan UPT Biotechnology Co.,Ltd
    Website：www.hnntwy.com Servive hotline :4006916686
    E-mail：service@uptbio.com
    Address：
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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