其他名稱: DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme)
功能: DNA metabolic process,?DNA replication,?DNA topological change,?DNA ligation,?DNA repair,?DNA packaging,?apoptosis,response to DNA damage stimulus,?nucleus organization,?chromosome segregation,?intracellular signaling cascade,?cell death,?regulation of cell death,?positive regulation of cell death,?programmed cell death,?death,?second-messenger-mediated signaling,?chromosome condensation,?apoptotic nuclear changes,?apoptotic chromosome condensation,cellular response to stress,?regulation of apoptosis,?positive regulation of apoptosis,?regulation of programmed cell death,?positive regulation of programmed cell death,?regulation of viral genome replication,?positive regulation of viral genome replication,?regulation of retroviral genome replication,?positive regulation of retroviral genome replication,phosphoinositide-mediated signaling,?positive regulation of viral reproduction,?regulation of viral reproduction,chromosome organization,
組織表達: Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung (PubMed:9155056). Also found in high-grade lymphomas, squamous cell lung tumors and seminomas (PubMed:9155056).
其他名稱: DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme)
功能: DNA metabolic process,?DNA replication,?DNA topological change,?DNA ligation,?DNA repair,?DNA packaging,?apoptosis,response to DNA damage stimulus,?nucleus organization,?chromosome segregation,?intracellular signaling cascade,?cell death,?regulation of cell death,?positive regulation of cell death,?programmed cell death,?death,?second-messenger-mediated signaling,?chromosome condensation,?apoptotic nuclear changes,?apoptotic chromosome condensation,cellular response to stress,?regulation of apoptosis,?positive regulation of apoptosis,?regulation of programmed cell death,?positive regulation of programmed cell death,?regulation of viral genome replication,?positive regulation of viral genome replication,?regulation of retroviral genome replication,?positive regulation of retroviral genome replication,phosphoinositide-mediated signaling,?positive regulation of viral reproduction,?regulation of viral reproduction,chromosome organization,
組織表達: Expressed in the tonsil, spleen, lymph node, thymus, skin, pancreas, testis, colon, kidney, liver, brain and lung (PubMed:9155056). Also found in high-grade lymphomas, squamous cell lung tumors and seminomas (PubMed:9155056).