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Phospho Survivin (T34) Cell-Based Colorimetric ELISA Kit
商品貨號： PLA000339
適 應 性： 人,小鼠,大鼠
ELISA
￥600元
規(guī)格：
在線咨詢
MSDS
說明書
商品描述
  • 發(fā)貨日期： 14
  • 基因名稱： BIRC5
  • Human_gene_id： 332
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=332
  • Human_swiss_prot_no： O15392
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O15392/entry
  • Mouse_swiss_prot_no： O70201
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O70201
  • Rat_swiss_prot_no： Q9JHY7
  • Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q9JHY7
  • 儲存： 2-8°C/6 months
  • 說明書： KA1337C.pdf
  • 其他名稱： Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
  • 功能： cell cycle checkpoint,?G2/M transition of mitotic cell cycle,?M phase of mitotic cell cycle,?mitotic cell cycle,?M phase,nuclear division,?cytokinesis,?apoptosis,?anti-apoptosis,?cell cycle,?chromosome segregation,?mitosis,?regulation of exit from mitosis,?regulation of mitotic cell cycle,?cell death,?negative regulation of peptidase activity,?regulation of cell cycle process,?regulation of cell death,?programmed cell death,?death,?cell cycle process,?cell cycle phase,?protein complex localization,?positive regulation of exit from mitosis,?spindle checkpoint,?regulation of apoptosis,?negative regulation of apoptosis,?regulation of programmed cell death,?negative regulation of programmed cell death,?negative regulation of catalytic activity,?negative regulation of caspase activity,?regulation of caspase activity,?negative regulation of molecular function,?positive regulation of cell cycle,?positive regulation of mitotic cell cycle,?organelle fission,chromosome localization,?cell division,?establishment of chromosome localization,?interphase,?interphase of mitotic cell cycle,?regulation of hydrolase activity,?negative regulation of hydrolase activity,?organelle localization,?establishment of organelle localization,?regulation of cell cycle,?regulation of peptidase activity,?regulation of endopeptidase activity,negative regulation of cell death,
  • 相關產(chǎn)品： YT4473,YT4472,YP1132,YP0319,YM3419,YM3386,KA4296C,KA1337C
  • 細胞定位： Cytoplasm . Nucleus . Chromosome . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Midbody . Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody (PubMed:11084331). Colocalizes with AURKB at mitotic chromosomes (PubMed:14610074). Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1-mediated nuclear export (PubMed:20826784). .
  • 組織表達： Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed:16329164). Also expressed in various renal cell carcinoma cell lines (PubMed:10626797). Expressed in cochlea including the organ of Corti, the lateral wall, the interdental cells of the Limbus as well as in Schwann cells and cells of the cochlear nerve and the spiral ganglions (at protein level). Not expressed in cells of the inner and outer sulcus or the Reissner's membrane (at protein level) (PubMed:21364656, PubMed:20627126).
  • 科研貨號： PLA000339
Phospho Survivin (T34) Cell-Based Colorimetric ELISA Kit
Catalog No PLA000339
Product information
  • 發(fā)貨日期： 14
  • 基因名稱： BIRC5
  • Human_gene_id： 332
  • Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=332
  • Human_swiss_prot_no： O15392
  • Human_swiss_link： http://www.uniprot.org/uniprotkb/O15392/entry
  • Mouse_swiss_prot_no： O70201
  • Mouse_swiss_link： http://www.uniprot.org/uniprot/O70201
  • Rat_swiss_prot_no： Q9JHY7
  • Rat_swiss_link： http://www.uniprot.org/uniprot/O54941Q9JHY7
  • 儲存： 2-8°C/6 months
  • 說明書： KA1337C.pdf
  • 其他名稱： Baculoviral IAP repeat-containing protein 5 (Apoptosis inhibitor 4) (Apoptosis inhibitor survivin)
  • 功能： cell cycle checkpoint,?G2/M transition of mitotic cell cycle,?M phase of mitotic cell cycle,?mitotic cell cycle,?M phase,nuclear division,?cytokinesis,?apoptosis,?anti-apoptosis,?cell cycle,?chromosome segregation,?mitosis,?regulation of exit from mitosis,?regulation of mitotic cell cycle,?cell death,?negative regulation of peptidase activity,?regulation of cell cycle process,?regulation of cell death,?programmed cell death,?death,?cell cycle process,?cell cycle phase,?protein complex localization,?positive regulation of exit from mitosis,?spindle checkpoint,?regulation of apoptosis,?negative regulation of apoptosis,?regulation of programmed cell death,?negative regulation of programmed cell death,?negative regulation of catalytic activity,?negative regulation of caspase activity,?regulation of caspase activity,?negative regulation of molecular function,?positive regulation of cell cycle,?positive regulation of mitotic cell cycle,?organelle fission,chromosome localization,?cell division,?establishment of chromosome localization,?interphase,?interphase of mitotic cell cycle,?regulation of hydrolase activity,?negative regulation of hydrolase activity,?organelle localization,?establishment of organelle localization,?regulation of cell cycle,?regulation of peptidase activity,?regulation of endopeptidase activity,negative regulation of cell death,
  • 相關產(chǎn)品： YT4473,YT4472,YP1132,YP0319,YM3419,YM3386,KA4296C,KA1337C
  • 細胞定位： Cytoplasm . Nucleus . Chromosome . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Midbody . Localizes at the centromeres from prophase to metaphase, at the spindle midzone during anaphase and a the midbody during telophase and cytokinesis. Accumulates in the nucleus upon treatment with leptomycin B (LMB), a XPO1/CRM1 nuclear export inhibitor (By similarity). Localizes on chromosome arms and inner centromeres from prophase through metaphase. Localizes to kinetochores in metaphase, distributes to the midzone microtubules in anaphase and at telophase, localizes exclusively to the midbody (PubMed:11084331). Colocalizes with AURKB at mitotic chromosomes (PubMed:14610074). Acetylation at Lys-129 directs its localization to the nucleus by enhancing homodimerization and thereby inhibiting XPO1/CRM1-mediated nuclear export (PubMed:20826784). .
  • 組織表達： Expressed only in fetal kidney and liver, and to lesser extent, lung and brain (PubMed:10626797). Abundantly expressed in adenocarcinoma (lung, pancreas, colon, breast, and prostate) and in high-grade lymphomas (PubMed:14741722, PubMed:16329164). Also expressed in various renal cell carcinoma cell lines (PubMed:10626797). Expressed in cochlea including the organ of Corti, the lateral wall, the interdental cells of the Limbus as well as in Schwann cells and cells of the cochlear nerve and the spiral ganglions (at protein level). Not expressed in cells of the inner and outer sulcus or the Reissner's membrane (at protein level) (PubMed:21364656, PubMed:20627126).
  • 科研貨號： PLA000339
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